Indigenous peoples all over the world have adverse relationships with research and researchers. Historically, research involving Indigenous peoples is conducted at the intersection of colonialism and asymmetrical power relations amongst researchers, industries, colonial states, and other stakeholders. The importance of research in shaping the policy agenda for development, access to health, basic infrastructure and for the empowerment of communities for self-determination is not lost on Indigenous peoples. Indigenous peoples and many other local and marginalized communities have been proverbial guinea pigs for researchers, being ‘used’ as research subjects whose rights were abused without consequences. Regarded as docile subjects, their voices were hardly heard, making them one of the most researched and yet underrepresented demographics in research.